The Reproducibility of Blood Acid Base Responses in Male Collegiate Athletes Following Individualised Doses of Sodium Bicarbonate: A Randomised Controlled Crossover Study

Gough, Lewis, Deb, Sanjoy, Sparks, Andy and McNaughton, Lars (2017) The Reproducibility of Blood Acid Base Responses in Male Collegiate Athletes Following Individualised Doses of Sodium Bicarbonate: A Randomised Controlled Crossover Study. Sports Medicine, 47 (10). pp. 2117-2127. ISSN 0112-1642 DOI https://doi.org/10.1007/s40279-017-0699-x

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Abstract

Abstract: Current evidence has suggested an individualised NaHCO3 ingestion strategy may be the most appropriate method to elicit a state of peak alkalosis. Such a strategy has displayed large interindividual variation (range 10-180 min) and if such a strategy is to be practically applied, the blood analyte response needs to be reproducible. Therefore, this study aimed to evaluate the reproducibility of blood pH, HCO3- and Na+ following acute NaHCO3 ingestion on more than one occasion. Fifteen team sports players completed six randomised trials entailing ingestion of 0.2 g.kg-1 BM NaHCO3 (SBC2a and b) twice, 0.3 g.kg-1 BM NaHCO3 (SBC3a and b) twice, or two control trials (CON1a and b) on separate days. Blood analysis included pH, HCO3- and Na+ prior to and at regular time points following NaHCO3 ingestion over a three hour period. Compared to pH, a greater relationship for HCO3- in both time to peak (HCO3- SBC2 = 0.772, P = 0.003, SBC3 = 0.942, P <0.001; pH SBC2 = 0.618, P = 0.044 SBC3 = 0.712, P = 0.016) and absolute change (HCO3- SBC2 = 0.890, P <0.001, SBC3 = 0.755, P = 0.008; pH SBC2 = 0.842, P = 0.001, SBC3 = 0.624, P = 0.041) was observed. Our results indicate both time to peak and absolute change in HCO3- is more reliable compared to pH. Future work should utilise an individualised NaHCO3 ingestion strategy based on HCO3- responses and evaluate the effects on exercise performance.

Item Type: Article
Uncontrolled Keywords: Buffers, bicarbonate, alkalosis, metabolism, individual response
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Sports Science
Date Deposited: 28 Feb 2017 11:55
URI: http://repository.edgehill.ac.uk/id/eprint/8759

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