Items where Author is "Tagalakis, Aristides"

Up a level
Export as [feed] RSS
Group by: Item Type | No Grouping
Jump to: Article
Number of items: 18.

Article

[img]
Preview
Mohammadi, A., Kudsiova, L., Mustapa, M F M., Campbell, F., Vlaho,, D., Welser, K., Storey, H., Tagalakis, Aristides, Hart, S L., Barlow, D J., Tabor, A B., Lawrence, M J. and Hailes, H C. (2019) The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems. Organic & Biomolecular Chemistry, 17 (4). pp. 945-957. ISSN 1477-0520 DOI https://doi.org/10.1039/c8ob02374c

[img]
Preview
Tagalakis, Aristides, Madaan, Shivam, Larsen, Scott D., Neubig, Richard R., Khaw, Peng T. and Yu-Wai-Man, Cynthia (2018) In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis. Journal of Nanobiotechnology, 16 (97). ISSN 1477-3155 DOI https://doi.org/10.1186/s12951-018-0425-3

[img]
Liang, Yaoyao, Peng, Jiahui, Li, Ning, Yu-Wai-Man, Cynthia, Wang, Qian, Xu, Yuhong, Wang, Hongxia, Tagalakis, Aristides and Zixiu, Du (2018) Smart nanoparticles assembled by endogenous molecules for siRNA delivery and cancer therapy via CD44 and EGFR dual-targeting. Nanomedicine, 15 (1). pp. 208-217. ISSN 1549-9634 DOI https://doi.org/10.1016/j.nano.2018.09.018

[img]
Preview
Fernando, Owen, Tagalakis, Aristides, Awwad, Sahar, Brocchini, Steve, Khaw, Peng T., Hart, Stephen L. and Yu-Wai-Man, Cynthia (2018) Development of targeted siRNA nanocomplexes to prevent fibrosis in experimental glaucoma filtration surgery. Molecular Therapy. ISSN 1525-0016 DOI https://doi.org/10.1016/j.ymthe.2018.09.004

[img]
Preview
[img]
Preview
Tagalakis, Aristides, Mynue, MM, Ivanova, H Chen, Smith, CM, Aldossary, AM and Rosa, LZ (2018) Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung. Thorax. pp. 1-10. ISSN 0040-6376 DOI https://doi.org/10.1136/thoraxjnl-2017-210670

[img]
Preview
[img]
Preview
Yu-Wai-Man, Cynthia, Tagalakis, Aristides, Meng, Jinhong, Lee, Richard M H., Bouremel, Yann, Virasami, Alex, Hart, Stephen L. and Khaw, Peng T. (2017) IL-6 and PRG4 are novel predictive and mechanistic tissue biomarkers in conjunctival fibrosis. JAMA Ophthalmology, 135 (11). pp. 1147-1155. ISSN 2168-6165 DOI https://doi.org/10.1001/jamaophthalmol.2017.3407

[img]
Preview
Yu-Wai-Man, Cynthia, Owen, Nicholas, Lees, Jonathan, Tagalakis, Aristides, Hart, Stephen L., Brocchini, S, Orengo, Christine, A. and Khaw, Peng T. (2017) Genome-wide RNA-Sequencing analysis reveals a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery. Scientific Reports (7). p. 5644. ISSN 2045-2322 DOI https://doi.org/10.1038/s41598-017-05780-5

[img]
Preview
Manunta, Maria, Tagalakis, Aristides, Attwood, Martin, Aldossary, Ahmed M., Weng, Alexander, Barnes, Josephine L., Munye, Mustafa M., McAnulty, Robin, J. and Hart, Stephen L. (2017) SiRNA delivery of ENAC mediated by targeted nanocomplex: a therapeutic strategy for cystic fibrosis. Scientific Reports, 7. p. 700. ISSN 2045-2322 DOI https://doi.org/10.1038/s41598-017-00662-2

[img]
Preview
[img]
Preview
Tagalakis, Aristides, Maeshima, R., Yu-Wai-Man, C., Meng, J., Syed, F., Wu, L., McCarthey, D., Aldossary, A.M., Moghimi, S.M. and Hart, S.L. (2017) Peptide and nucleic acid-directed self-assembly of cationic nanovehicles through giant unilamellar vesicle modification: targetable nanocomplexes for in vivo nucleic acid delivery. Acta Biomaterialia, 51. pp. 351-362. ISSN 1742-7061 DOI https://doi.org/10.1016/j.actbio.2017.01.048

[img]
Munye, Mustafa M., Tagalakis, Aristides, Barnes, Josephine L., Brown, Rachel E., McAnulty, Robin J., Howe, Steven J. and Hart, Stephen L. (2016) Minicircle DNA provide enhanced and prolonged transgene expression following airway gene transfer. Scientific Reports, 6. p. 23125. ISSN 2045-2322 DOI https://doi.org/10.1038/srep23125

[img]
Yu-Wai-Man, Cynthia, Tagalakis, Aristides, Manunta, Maria D., Bailly, M, Hart, Stephen L. and Khaw, Peng T. (2016) Receptor-targeted liposome-peptide-siRNA nanoparticles represent a novel and efficient therapeutic approach to prevent conjunctival fibrosis. Scientific Reports, 6. p. 21881. ISSN 2045-2322 DOI https://doi.org/10.1038/srep21881

[img]
Preview
Kwok, Albert, McCarthy, David, Hart, Stephen L. and Tagalakis, Aristides (2016) Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNA. Chemical Biology and Drug Design, 87 (5). pp. 747-763. ISSN 1747-0277 DOI https://doi.org/10.1111/cbdd.12709

[img]
Preview
Tagalakis, Aristides, Castellaro, S, Zhou, H, Bienemann, A, Munye, M.M., McCarthy, D, White, E.A. and Hart, S.L. (2015) A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency. International Journal of Nanomedicine, 10. pp. 2673-2683. ISSN 1176-9114 DOI https://doi.org/10.2147/IJN.S78935

[img]
Preview
Munye, M.M., Ravi, J, Tagalakis, Aristides, McCarthy, D, Ryadnov, M.G. and Hart, S.L. (2015) Role of liposome and peptide in the synergistic enhancement of transfection with a lipopolyplex vector. Scientific Reports, 5 (9292). ISSN 2045-2322 (online) DOI https://doi.org/10.1038/srep09292

Weng, A, Manunta, M, Thakur, M, Gilabert-Oriol, R, Tagalakis, Aristides, Eddaoudi, A, Munye, M.M., Vink, C.A., Wiesner, B, Eichhorst, J, Melzig, M.F. and Hart, S.L. (2015) Improved intracellular delivery of peptide- and lipid- nanoplexes by natural glycosides. Journal of Controlled Release, 206. pp. 75-90. ISSN 0168-3659 DOI https://doi.org/10.1016/j.jconrel.2015.03.007

[img]
Preview
Du, Zixiu, Munye, M.M., Tagalakis, Aristides, Manunta, M.D. and Hart, S.L. (2014) The role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulations. Scientific Reports, 4. p. 7107. ISSN 2045-2322 DOI https://doi.org/10.1038/srep07107

[img]
Preview
Tagalakis, Aristides, Lee, D.H., Bienemann, A.S., Zhou, H, Munye, M.M., Saraiva, L, McCarthy, D, Du, Z, Vink, C.A., Maeshima, R, White, E.A., Gustafsson, K and Hart, S.L. (2014) Multifunctional, self-assembling, anionic peptide-lipid nanocomplexes for targeted siRNA delivery. Biomaterials, 35 (29). pp. 8406-8415. ISSN 0142-9612 DOI https://doi.org/10.1016/j.biomaterials.2014.06.003

[img]
Preview
Tagalakis, Aristides, Kenny, G, Bienemann, A.S., McCarthy, D, Munye, M.M., Taylor, H, Wyatt, M.J., Lyhtgoe, M.F., White, E.A. and Hart, S.L. (2014) PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes. Journal of Controlled Release, 174. pp. 177-187. ISSN 0168-3659 DOI i0.1016/j.jconrel.2013.11.014